Comparison of THP-1 subtypes reveals differences on transcriptomic and protein expression level throughout their immunological differentiation

  • Published:17. Aug 2026
  • Authors:Sabine Klatt, Gudrun Marquardt, Miriam Faxel, Stefan Rubner, Ioannis Papasotiriou

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Adaptation of non-invasive cancer cells to 3D collagen I microenvironment induces transcriptional reprogramming accompanied by a more complex RNA landscape

  • Published:1. Aug 2026
  • Authors:Theresa Wießner-Kroh, Stefanie Hübschmann, Gudrun Marquardt, Jennifer Szczesny, Miriam Faxel, Stefan Rubner, and Ioannis Papasotiriou

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Comparative binding and activity analysis of known serine hydroxymethyltransferase inhibitors in biochemical assays

  • Published:2. Jul 2026
  • Authors:Julian Gräb, Christine Wagner, Charlotte Beber, Jennifer Szczesny, Stefan Rubner, Ioannis Papasotiriou

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Long-term cultivation shifts transcriptomic profile of HCT-116 cells

  • Published:22. Apr 2026
  • Authors:Gudrun Marquardt, Theresa Wießner-Kroh, Stefan Rubner, and Ioannis Papasotiriou

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The continual problem of crossing survival curves in clinical trial analysis and methods for effectively addressing it: A narrative review

  • Published:3. Nov 2025
  • Authors:Beis, George; Papasotiriou, Ioannis

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Tailoring treatment for advanced and/or recurrent ovarian cancer using the response of circulating tumor cells to therapy: a retrospective analysis

  • Published:31. Oct 2025
  • Authors:Lyri Adar, Eliya Shachar, Ido Laskov, Nadav Michaan, Adi Diner, Gilat Rotkop, Galya Basol Kochav, Ido Wolf, Tamar Safra

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Assessment of Protein Expression and Enumeration of Circulating Tumor Cells in Various Cancer Types

  • Published:24. Oct 2025
  • Authors:Iliopoulos A., Hatzidaki E., Apostolou P., Papasotiriou I.

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Cell fusion model to investigate a potential origin of circulating tumor cells

  • Published:24. Sep 2025
  • Authors:Sabine Klatt, Theresa Wießner-Kroh, Gudrun Marquardt, Miriam Faxel, Stefan Rubner, Ioannis Papasotiriou

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Enumeration and Immunophenotype of Circulating Tumor Cells in Colorectal Cancer Patients

  • Published:7. Jul 2025
  • Authors:Paz A., Iliopoulos A., Apostolou P.,Hatzidaki E., Papasotiriou I.

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Second-line therapy adjustment for advanced pancreatic cancer using circulating tumor cells: Preliminary results

  • Published:20. Jun 2025
  • Authors:Joachim Drevs, Mandeep Singh Malhotra, Huseyin Sahinbas, Aggelos Iliopoulos, George Beis, Panagiotis Apostolou, Ioannis Papasotiriou

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Adjusting treatment strategies using circulating tumor cells: preliminary results on metastatic colorectal cancer

  • Published:1. Feb 2025
  • Authors:Joachim Drevs, Mandeep Singh Malhotra, Huseyin Sahinbas, Aggelos Iliopoulos, George Beis, Panagiotis Apostolou And Ioannis Papasotiriou

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Evaluation of the effect of benzaldehyde derivatives in human cancer cells

  • Published:18. Oct 2024
  • Authors:Papanikolaou A., Hatzidaki E., Apostolou P., Papasotiriou I.

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Find out more about the scientific basis of RGCC tests