Scientists have developed a new oral DPP inhibitor that, when used in combination with targeted immunotherapy, has shown promise at treating pancreatic cancer. In trials, the combination therapy proved to be successful at increasing the number of cancer-killing cells around a tumour, reducing its growth and, in some cases, eliminating cancer altogether. The authors believe […]
We are delighted to announce the launch of a brand-new branch office dedicated to serving the needs of RGCC Network doctors in North America. RGCC International – North America has been launched in response to a period of sustained and exponential growth in this region. The team will continue to deliver excellent customer service to […]
Chemotherapy drugs could enhance the spread of cancer beyond a primary tumour site, scientists have established. In tests, researchers found that mice injected with cyclophosphamide, a popular chemotherapy drug, enabled breast cancer cells to squeeze through the blood vessel linings in the lungs and stick to cell walls. While chemotherapy remains an effective treatment for […]
Mutations in cancer-suppressing genes that block cell growth may explain why some cancers evade the body’s immune system, scientists have established. A US team has identified 100 “mutated tumor suppressor genes” that affect the body’s ability to spot and destroy cancer cells in mice. While at an early stage, identifying genetic mutations could lead to […]
Scientists have identified a new synthetic molecular code that could improve a patient’s response to an effective cancer treatment, known as PD-1 blockade immunotherapy. The team from Kyoto University have created a new molecular code that ensures a supply of energy to cancer-killing T-cells. The molecular code is highly effective at targeting cancer cells when […]
Researchers have identified a key enzyme that cancerous tumours rely on to grow and spread within the body. Described as cancer’s “Achilles Heel”, scientists believe that targeting this enzyme stops tumour cells from growing and spreading. The findings could accelerate the development of new treatments for solid-tumour cancers. Solid cancerous tumours rely on an available […]
Combining circulating tumour DNA (ctDNA) with magnetic resonance imaging (MRI) can more accurately predict the likelihood of locally advanced rectal cancer (LARC) returning after treatment, Chinese scientists have found. In a new study published in PLOS Medicine, researchers describe how combining the techniques improved diagnosis and could improve treatment and outcomes for patients. In addition, […]
The presence of circulating tumour DNA (ctDNA) is a crucial biomarker for patients with bladder cancer (urothelial carcinoma) researchers have found in a new study. Scientists suggest that post-operative screening for ctDNA could improve cancer treatments and patient outcomes. The authors hope the findings could help improve outcomes for bladder cancer and more broadly illustrates […]
Patients with advanced colorectal cancer can benefit from treatment with advanced immunotherapy, known as immune checkpoint inhibitor PD-1/PD-L1, scientists have discovered. The findings provide new hope for colorectal cancer patients and more broadly demonstrate the incredible potential for immunotherapies to extend life and treat all forms of cancer. If chemotherapy fails, patients with microsatellite stable […]
An advanced cancer therapy developed by RGCC scientists has been categorised as a Cell Therapy Medicinal Product (CTMP) by the European Medicines Agency (EMA). Tested on breast cancer cells but effective at treating all forms of the disease, the adoptive T cell-based therapy encourages the body’s immune system to target cancer cells. Due to enter clinical trials […]
Activating protein p53 can boost a patient’s immune response against cancerous tumours, researchers at Sweden’s Karolinska Institutet have discovered. Using a commercially available substance known as ALRN-6924, the team successfully generated an anti-tumour immune response. The finding improves our understanding of the crucial role p53 plays in tumour development. In the future, it could help […]
RGCC researchers have developed a new approach to tackling COVID-19 (SARS-CoV-2) that could form the basis of a new treatment option. Laboratory tests have established that the new treatments were effective at inhibiting the spread of the disease. The next stage will see them progress to develop a drug delivery system, a further step before […]
